As of Plasma 6.7.4, you can tweak the most used network parameters, including adding VPN profiles, using the GUI in Plasma settings.
An important parameter, which I believe should be included in the configuration page for wired networks, is 802-3-ethernet.wake-on-lan.
I know that enabling Wake on LAN (if supported) should be as simple as running
nmcli connection modify "Wired network X" 802-3-ethernet.wake-on-lan magic
but I think that this option should be directly visible to the users, maybe with the addition of a simple warning to check BIOS settings (in my case I need to have resume by PCI-e enabled for the magic packets to work properly).
Similarly, the same could be done with 802-11-wireless.wake-on-wlan, but support for WoWLAN might be more limited than simple WoL. The hardware must support it as well as the drivers, and power-saving settings have to be set accordingly (if the BIOS even allows it). Changing this parameter might not be enough to enable the feature, but we could show a similar warning to the one I mentioned above.