So I have 2 1080p displays, a 1440p 360hz monitor, and a Valve Index hooked up to my system. I had no trouble driving all of these at once, however with a recent update, once I start up either Monado or SteamVR, it brings my session down to its knees. My cursor remains active, but windows will take seconds to refresh or move around.
I tested my spare Quest 2 with WiVRn and ALVR, which seemed to work fine. I also unplugged 2 of my monitors to find the session was smooth again, so the problem seems to be exclusive to wired HMDs on multi-monitor setups