Base Fedora KDE Plasma 6.5.2, at some point clicking on something within the System Tray or the App Launcher will not allow whatever popup associated with what’s clicked on to expand past the panel, thus making whatever functions saught after unuseable w/out restarting plasmashell and hoping it doesn’t happen again.
if this is reproducible after a reboot, then it should be reported to bugs.kde.org
try a new panel with a system tray widget added and see if that shows this behavior.