Back in the day, we had keyboards that had 24 function keys. 122 key keyboards
When we moved from dumb terminals to PCs and accessing the mainframes and AS/400s, we ended up with 102 key keyboards, but if you needed to use the F13 through F24, you had to use CTL+F1 to make F13, so if any of your shortcut keys are using CTL+Fx then there will be some conflict.
You should be able to remap those key combos to whatever you choose.