Unless you are on Debian Stable, which probably still uses ALSA (or OSS) 
.
Since Pipewire and, for that use case additionally but usually installed with it, Wireplumber has matured:
Nobody prevents you from.
Seriously that “ALC312 Audio” and “VG4451215” or something alike for the monitor(s) only nagged me for 5 seconds, another 5 seconds later google showed the solution.
Some could argue handcrafting your own config text file is not suited for “normal mօrtals” but as far I remember that should still be easier than doing the same on Windows. 
Edit: Looks like, from the thread about its release, with Plasma 6.2 things are changing. Not sure if that means, more easily freely editable or (more) fixed to something from what I don’t know how reasonable for my setup / liking yet. Have to wait until 6.2 arrives on Arch.